HomeABSTRACT
Antibiotics are a class of drugs that most widely used in the world related to the number of occurrences of bacterial infection. More than a quarter of hospital budgets spent on the cost of antibiotic use. The most dangerous of the negative impact of irrational use of antibiotics is the occurrence of antibiotic resistance. WHO and several organizations have issued statements about the importance of assessing the factors associated with the issue, including strategies for controlling the incidence of resistance to prevent the development of germs resistant to the community.
This study aims to determine the use of antibiotics with the ATC / DDD system and Gyssens’s Criteria in Ward Internal Medicine department of DR. M. Djamil Padang. The study was conducted with the design of observational studies using cross-sectional design. Retrieval of data prospectively who received antibiotics from February to April is calculated using one-sample situation. From 50 patients who received antibiotics, then quantitatively evaluated with the ATC / DDD system and qualitative evaluation with Gyssens’s criteria.
The results of studies of antibiotic use with the ATC/DDD system are Ceftriaxone 38.955DDD/100patient-days, Sefotaksim14,363DDD/100 patient-days, Ciprofloxacin 11.600DDD/100patient-days, Metronidazole 13.240DDD/100patient-days, Meropenem 3.808DDD/patient-days, Seftazidim 2.013DDD/100 patient-days, Gentamicin 0.507 DDD/100patient-days, Ampicillin 2.013DDD/100patient-days, Isoniazid 6.311DDD/100patient-days, Rifampicin 4.733DDD/100patient-days, Pyrazinamide 4.207DDD/100patient-days, Ethambutol 3.945DDD/100patient-days and Cotrimoxazole 4.244 DDD/100patient-days.
Meanwhile, the study of antibiotic use with Gyssens’s criteria derived category I (appropiate / rational) 43.81%, IIA (not appropriate dosage) 0.95%, IIIA (duration of antibiotic is too long) 14.29%, IIIB (duration of antibiotic is too short) 2 , 86%, IVA (more effective antibiotics) 10.48%, IVD (antibiotics with narrower spectrum) 9.52%, V (no indication of the use of antibiotics) 18.09%.
